Reversal of cardiac iron loading and dysfunction in thalassemic mice by curcuminoids

Non-transferrin bound iron (NTBI) is found in plasma of β-thalassemia patients and causes oxidative tissue damage. Cardiac siderosis and complications are the secondary cause of death in β-thalassemia major patients. Desferrioxamine (DFO), deferiprone (DFP) and deferasirox (DFX) are promising chelat...

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Bibliographic Details
Main Authors: Thephinlap C., Phisalaphong C., Lailerd N., Chattipakorn N., Winichagoon P., Vadolus J., Fucharoen S., Porter J.B., Srichairatanakool S.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-78751479300&partnerID=40&md5=784a8d5e002348796d4084e9c4dc0243
http://www.ncbi.nlm.nih.gov/pubmed/21235521
http://cmuir.cmu.ac.th/handle/6653943832/2723
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Institution: Chiang Mai University
Language: English

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