Telomere shortening and cell senescence induced by perylene derivatives in A549 human lung cancer cells
Cancer cells evade replicative senescence by re-expressing telomerase, which maintains telomere length and hence chromosomal integrity. Telomerase inhibition would lead cancer cells to senesce and therefore prevent cancer cells from growing indefinitely. G-quadruplex ligands can attenuate telomerase...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2014
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| Online Access: | http://www.scopus.com/inward/record.url?eid=2-s2.0-84873312526&partnerID=40&md5=b55d40a92e31ccb4ff50cacfcac3b9c2 http://www.ncbi.nlm.nih.gov/pubmed/23321015 http://cmuir.cmu.ac.th/handle/6653943832/4017 |
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| Institution: | Chiang Mai University |
| Language: | English |