Effects of iron overload, an iron chelator and a T-Type calcium channel blocker on cardiac mitochondrial biogenesis and mitochondrial dynamics in thalassemic mice

• Main Authors: Khamseekaew J., Kumfu S., Wongjaikam S., Kerdphoo S., Jaiwongkam T., Srichairatanakool S., Fucharoen S., Chattipakorn S., Chattipakorn N.
• Format: Journal
• Published: 2017
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85012924821&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/40958
• Institution: Chiang Mai University

© 2017 Elsevier B.V. Although cardiac mitochondrial dysfunction is involved in the pathophysiology of iron-overload cardiomyopathy, the precise mechanisms of iron-induced mitochondrial dysfunction, and the roles of the iron chelator deferiprone and the T-type calcium channel blocker efonidipine on c...