Differential chemosensitization of P-glycoprotein overexpressing K562/Adr cells by withaferin A and Siamois polyphenols
Background: Multidrug resistance (MDR) is a major obstacle in cancer treatment and is often the result of overexpression of the drug efflux protein, P-glycoprotein (P-gp), as a consequence of hyperactivation of NFκB, AP1 and Nrf2 transcription factors. In addition to effluxing chemotherapeutic drugs...
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Main Authors: | Suttana W., Mankhetkorn S., Poompimon W., Palagani A., Zhokhov S., Gerlo S., Haegeman G., Berghe W. |
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格式: | 雜誌 |
出版: |
2017
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在線閱讀: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77953552264&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/43311 |
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機構: | Chiang Mai University |
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