Pharmaco/ferrokinetic-related pro-oxidant activity of deferiprone in β-thalassemia

The potential of free radical formation in serum of β-thalassemia/ Hb E patients receiving a single oral dose of 25 mg/kg body weight of deferiprone, a bidentate orally active iron chelator, was evaluated using EPR/spin trapping technique. In the presence of ascorbic acid and tert-butylhydroperoxide...

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Bibliographic Details
Main Authors: Totsapol Jirasomprasert, Noppawan Phumala Morales, Lie M G Limenta, Srisuporn Sirijaroonwong, Paveena Yamanont, Prapin Wilairat, Suthat Fucharoen, Udom Chantharaksri
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/27177
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Institution: Mahidol University

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