Development of a Novel Anti-CD19 CAR Containing a Fully Human scFv and Three Costimulatory Domains
Second-generation anti-CD19-chimeric antigen receptor T cells (anti-CD19-CAR2 T cells) are effective for treating B-cell malignancies; however, anti-CD19-CAR2 T cells can induce human anti-mouse immune responses because anti-CD19 single-chain variable fragment (scFv) in the CAR molecules is derived...
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Main Author: | Wutti-in Y. |
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Other Authors: | Mahidol University |
Format: | Article |
Published: |
2023
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/83858 |
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Institution: | Mahidol University |
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