Defining neutralization and allostery by antibodies against COVID-19 variants

by Tulsian, Nikhil Kumar, Palur, Raghuvamsi Venkata, Qian, Xinlei, Gu, Yue, Bhuvaneshwari D/O Shunmuganathan, Samsudin, Firdaus, Wong, Yee Hwa, Lin, Jianqing, Purushotorman, Kiren, Kozma, Mary McQueen, Wang, Bei, Lescar, Julien, Wang, Cheng-I, Gupta, Ravindra Kumar, Bond, Peter John, MacAry, Paul Anthony
Published 2024

CD28-CAR-T cell activation through FYN kinase signaling rather than LCK enhances therapeutic performance

by Wu, Ling, Brzostek, Joanna, Vale, Previtha Dawn Sakthi, Wei, Qianru, Koh, Clara KT, Ong, June Xu Hui, Wu, Liang-zhe, Tan, Jia Chi, Chua, Yen Leong, Yap, Jiawei, Song, Yuan, Tan, Vivian Jia Yi, Tan, Triscilla YY, Lai, Junyun, MacAry, Paul A, Gascoigne, Nicholas RJ
Published 2023

Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A(star)11:01

by Gu, Yue, Wong, Yee Hwa, Liew, Chong Wai, Chan, Conrad EZ, Murali, Tanusya M, Yap, Jiawei, Too, Chien Tei, Purushotorman, Kiren, Hamidinia, Maryam, El Sahili, Abbas, Goh, Angeline TH, Teo, Rachel ZC, Wood, Kathryn J, Hanson, Brendon J, Gascoigne, Nicholas RJ, Lescar, Julien, Vathsala, Anantharaman, MacAry, Paul A
Published 2021

Finger stick blood test to assess postvaccination SARS-CoV-2 neutralizing antibody response against variants

by Lim, Sing Mei, Cheng, Hoi Lok, Jia, Huan, Kongsuphol, Patthara, Shunmuganathan, Bhuvaneshwari, Chen, Ming Wei, Ng, Say Yong, Gao, Xiaohong, Turaga, Shuvan Prashant, Heussler, Sascha P, Somani, Jyoti, Sengupta, Sharmila, Tay, Dousabel MY, McBee, Megan E, Young, Barnaby E, MacAry, Paul A, Sikes, Hadley D, Preiser, Peter R
Published 2022

Finger stick blood test to assess postvaccination SARS-CoV-2 neutralizing antibody response against variants

by Lim, Sing Mei, Cheng, Hoi Lok, Jia, Huan, Kongsuphol, Patthara, Bhuvaneshwari D/O Shunmuganathan, Chen, Ming Wei, Ng, Say Yong, Gao, Xiaohong, Turaga, Shuvan Prashant, Heussler, Sascha P., Somani, Jyoti, Sengupta, Sharmila, Tay, Dousabel M. Y., McBee, Megan E., Young, Barnaby Edward, MacAry, Paul A., Sikes, Hadley D., Preiser, Peter Rainer
Published 2023

Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01

by Gu, Yue, Wong, Yee Hwa, Liew, Chong Wai, Chan, Conrad E. Z., Murali, Tanusya M., Yap, Jiawei, Too, Chien Tei, Purushotorman, Kiren, Hamidinia, Maryam, El Sahili, Abbas, Goh, Angeline T. H., Teo, Rachel Z. C., Wood, Kathryn J., Hanson, Brendon J., Gascoigne, Nicholas R. J., Lescar, Julien, Vathsala, Anantharaman, MacAry, Paul A.
Published 2019

Employment of a high throughput functional assay to define the critical factors that influence vaccine induced cross-variant neutralizing antibodies for SARS-CoV-2

by Gu, Yue, Shunmuganathan, Bhuvaneshwari, Qian, Xinlei, Gupta, Rashi, Tan, Rebecca S. W., Kozma, Mary, Purushotorman, Kiren, Murali, Tanusya M., Tan, Nikki Y. J., Preiser, Peter Rainer, Lescar, Julien, Nasir, Haziq, Somani, Jyoti, Tambyah, Paul A., Smith, Kenneth G. C., Renia, Laurent, Ng, Lisa F. P., Lye, David C., Young, Barnaby E., MacAry, Paul A.
Published 2024

A rapid simple point-of-care assay for the detection of SARS-CoV-2 neutralizing antibodies

by Kongsuphol, Patthara, Jia, Huan, Cheng, Hoi Lok, Gu, Yue, Shunmuganathan, Bhuvaneshwari, Chen, Ming Wei, Lim, Sing Mei, Ng, Say Yong, Tambyah, Paul Ananth, Nasir, Haziq, Gao, Xiaohong, Tay, Dousabel, Kim, Seunghyeon, Gupta, Rashi, Qian, Xinlei, Kozma, Mary M, Purushotorman, Kiren, McBee, Megan E, MacAry, Paul A, Sikes, Hadley D, Preiser, Peter R
Published 2023

Blomia tropicalis-Specific TCR Transgenic Th2 Cells Induce Inducible BALT and Severe Asthma in Mice by an IL-4/IL-13-Dependent Mechanism

by Chua, Yen Leong, Liong, Ka Hang, Huang, Chiung-Hui, Wong, Hok Sum, Zhou, Qian, Ler, Say Siong, Tang, Yafang, Low, Chin Pei, Koh, Hui Yu, Kuo, I-Chun, Zhang, Yongliang, Wong, WS Fred, Peh, Hong Yong, Lim, Hwee Ying, Ge, Moyar Qing, Haczku, Angela, Angeli, Veronique, MacAry, Paul A, Chua, Kaw Yan, Kemeny, David M
Published 2023

Platelet TLR7 is essential for the formation of platelet-neutrophil complexes and low-density neutrophils in lupus nephritis

by Tay, Sen Hee, Zharkova, Olga, Lee, Hui Yin, Toh, Michelle Min Xuan, Libau, Eshele Anak, Celhar, Teja, Narayanan, Sriram, Ahl, Patricia Jennifer, Ong, Wei Yee, Joseph, Craig, Lim, Jeffrey Chun Tatt, Wang, Lingzhi, Larbi, Anis, Liang, Shen, Lateef, Aisha, Akira, Shizuo, Ling, Lieng Hsi, Thamboo, Thomas Paulraj, Yeong, Joe Poh Seng, Lee, Bernett Teck Kwong, Edwards, Steven W, Wright, Helen L, MacAry, Paul Anthony, Connolly, John E, Fairhurst, Anna-Marie
Published 2024

Platform for the interdisciplinary study of cardiovascular, metabolic and neurovascular diseases (PICMAN) protocol

by Dalakoti, Mayank, Leow, Melvin Khee Shing, Khoo, Chin Meng, Yang, Hayang, Ling, Lieng Hsi, Muthiah, Mark, Tan, Eunice, Lee, Jonathan, Dan, Yock Young, Chew, Nicholas, Seow, Wei Qiang, Soong, Poh Loong, Gan, Louis, Gurung, Rijan, Ackers-Johnson, Matthew, Hou, Han Wei, Sachaphibulkij, Karishma, MacAry, Paul, Low, Gwen, Ang, Christy, Yeo, Tee Joo, Djohan, Andie Hartanto, Li, Tony, Yeung, Wesley, Soh, Rodney, Sia, Ching Hui, Panday, Vinay, Loong, Shaun S. E., Tan, Benjamin Y. Q., Yeo, Leonard L. L., Teo, Lynette, Chow, Pierce, Foo, Roger
Published 2024

The Fc-mediated effector functions of a potent SARS-CoV-2 neutralizing antibody, SC31, isolated from an early convalescent COVID-19 patient, are essential for the optimal therapeut...

by Chan, Conrad E. Z., Seah, Shirley G. K., Chye, De Hoe, Massey, Shane, Torres, Maricela, Lim, Angeline P. C., Wong, Steven K. K., Neo, Jacklyn J. Y., Wong, Pui San, Lim, Jie Hui, Loh, Gary S. L., Wang, Dongling, Boyd-Kirkup, Jerome D., Guan, Siyu, Thakkar, Dipti, Teo, Guo Hui, Purushotorman, Kiren, Hutchinson, Paul E., Young, Barnaby E., Low, Jenny G., MacAry, Paul A., Hentze, Hannes, Prativadibhayankara, Venkateshan S., Ethirajulu, Kantharaj, Comer, Jason E., Tseng, Chien-Te K., Barrett, Alan D. T., Ingram, Piers J., Brasel, Trevor, Hanson, Brendon John
Published 2022

Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose

by Renia, Laurent, Goh, Yun Shan, Rouers, Angeline, Le Bert, Nina, Chia, Wan Ni, Chavatte, Jean-Marc, Fong, Siew-Wai, Chang, Zi Wei, Zhuo, Nicole Ziyi, Tay, Matthew Zirui, Chan, Yi-Hao, Tan, Chee Wah, Yeo, Nicholas Kim-Wah, Amrun, Siti Naqiah, Huang, Yuling, Wong, Joel Xu En, Hor, Pei Xiang, Loh, Chiew Yee, Wang, Bei, Ngoh, Eve Zi Xian, Salleh, Siti Nazihah Mohd, Carissimo, Guillaume, Dowla, Samanzer, Lim, Alicia Jieling, Zhang, Jinyan, Lim, Joey Ming Er, Wang, Cheng-I, Ding, Ying, Pada, Surinder, Sun, Louisa Jin, Somani, Jyoti, Lee, Eng Sing, Ong, Desmond Luan Seng, Leo, Yee-Sin, MacAry, Paul A, Lin, Raymond Tzer Pin, Wang, Lin-Fa, Ren, Ee Chee, Lye, David C, Bertoletti, Antonio, Young, Barnaby Edward, Ng, Lisa FP
Published 2022

Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose

by Renia, Laurent, Goh, Yun Shan, Rouers, Angeline, Bert, Nina Le, Chia, Wan Ni, Chavatte, Jean-Marc, Fong, Siew-Wai, Chang, Zi Wei, Zhuo, Nicole Ziyi, Tay. Matthew Zirui, Chan, Yi-Hao, Tan Chee Wah, Yeo, Nicholas Kim-Wah, Amrun, Siti Naqiah, Huang, Yuling, Wong, Joel Xu En, Hor, Pei Xiang, Loh, Chiew Yee, Wang, Bei, Ngoh, Eve Zi Xian, Salleh, Siti Nazihah Mohd Salleh, Carissimo, Guillaume, Dowla, Samanzer, Lim, Alicia Jieling, Zhang, Jinyan, Lim, Joey Ming Er, Wang, Cheng-I., Ding, Ying, Pada, Surinder, Sun, Lousia Jin, Somani, Jyoti, Lee, Eng Sing, Ong, Desmond Luan Seng, Leo, Yee-Sin, MacAry, Paul A., Lin, Raymond Tzer Pin, Wang, Lin-Fa, Ren, Ee Chee, Lye, David C., Bertoletti, Antonio, Young, Barnaby Edward, Ng, Lisa F. P., Ruesta, Torres Anthony, Neo, Vanessa, Chen, Wendy Yehui, Goh, Estelle Yi Wei, Ong, Alice Soh Meoy, Chua, Adeline Chiew Yen, Nguee, Samantha Yee Teng, Tan, Yong Jie, Tang, Weiyi
Published 2023