Synthesis of pyrazinamide analogs of aspirin
Pyrazinamide derivatives of aspirin (6a) and (6b) were synthesized. The synthesis involved teh Friedel Crafts acylation of methyl salicylate using the appropriate alkanoyl chloride and ZnCl2 as catalyst followed by hydrolysis to produce the precursor compounds (3a) and (3b). Compound (3a) was couple...
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Main Authors: | Alea, Glenn V., Lagua, Faith Marie G., Ajero, Michael Dominic M. |
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Format: | text |
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Animo Repository
2012
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Online Access: | https://animorepository.dlsu.edu.ph/faculty_research/7784 |
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Institution: | De La Salle University |
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