Widespread recognition of 5' splice sites by noncanonical base-pairing to U1 snRNA involving bulged nucleotides
An established paradigm in pre-mRNA splicing is the recognition of the 5′ splice site (5′ss) by canonical base-pairing to the 5′ end of U1 small nuclear RNA (snRNA). We recently reported that a small subset of 5′ss base-pair to U1 in an alternate register that is shifted by 1 nucleotide. Using genet...
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| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/100017 http://hdl.handle.net/10220/16284 |
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| Institution: | Nanyang Technological University |
| Language: | English |