N-hetereocyclic carbenes-catalyzed desymmetrization and rapid access to spirocylic molecules

• Main Author: Zhuo, Shitian
• Other Authors: Chi Robin Yonggui
• Format: Theses and Dissertations
• Language: English
• Published: 2019
• Subjects: DRNTU::Science::Chemistry::Organic chemistry::Organic analysis
• Online Access: https://hdl.handle.net/10356/103675; http://hdl.handle.net/10220/47436
• Institution: Nanyang Technological University

This thesis focuses on enantioselective desymmetrization reactions enabled by N-heterocyclic carbenes (NHCs) organocatalysts. It contains four parts: Chapter 1 gives brief introductions to the history and development of NHCs organocatalysts classified by active intermediates within this field. Repre...