Inhibitors of energy metabolism interfere with antibiotic-induced death in mycobacteria
Energy metabolism has recently gained interest as a target space for antibiotic drug development in mycobacteria. Of particular importance is bedaquiline (Sirturo), which kills mycobacteria by inhibiting the F1F0 ATP synthase. Other components of the electron transport chain such as the NADH dehydro...
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Main Authors: | Lee, Bei Shi, Kalia, Nitin Pal, Jin, Xin Er F., Hasenoehrl, Erik J., Berney, Michael, Pethe, Kevin |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2019
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/103762 http://hdl.handle.net/10220/48892 |
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Institution: | Nanyang Technological University |
Language: | English |
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