Acetylation at lysine 183 of progesterone receptor by p300 accelerates DNA binding kinetics and transactivation of direct target genes
The identification of lysine acetylation of steroid hormone receptors has previously been based on the presence of consensus motif (K/R)XKK. This study reports the discovery by mass spectrometry of a novel progesterone receptor acetylation site at Lys-183 that is not in the consensus motif. In vivo...
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Main Authors: | Sze, Siu Kwan, Chung, Hwa Hwa, Tay, Alvin Shun Long, Lin, Valerie Chun Ling |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2015
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/106716 http://hdl.handle.net/10220/25119 |
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Institution: | Nanyang Technological University |
Language: | English |
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