Aminomethylation of enals through carbene and acid cooperative catalysis : concise access to β2-amino acids

Aminomethylation of enals through carbene and acid cooperative catalysis : concise access to β2-amino acids

A convergent, organocatalytic asymmetric aminomethylation of α,β-unsaturated aldehydes by N-heterocyclic carbene (NHC) and (in situ generated) Brønsted acid cooperative catalysis is disclosed. The catalytically generated conjugated acid from the base plays dual roles in promoting the formation of az...

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書目詳細資料
Main Authors:	Chi, Robin Yonggui, Xu, Jianfeng, Chen, Xingkuan, Wang, Ming, Zheng, Pengcheng, Song, Bao-An
其他作者:	School of Physical and Mathematical Sciences
格式:	Article
語言:	English
出版:	2015
主題:	DRNTU::Science::Chemistry::Physical chemistry::Catalysis
在線閱讀:	https://hdl.handle.net/10356/107124 http://hdl.handle.net/10220/25281 http://dx.doi.org/10.1002/anie.201412132
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