Role of chaperones in selective autophagy of protein inclusions

• Main Author: Ng, Yan Ting
• Other Authors: Wong Siew Peng Esther
• Format: Student Research Poster
• Language: English
• Published: 2013
• Subjects: Protein aggregates; Macroautophagy
• Online Access: https://hdl.handle.net/10356/107538; http://hdl.handle.net/10220/9089
• Institution: Nanyang Technological University

Autophagy is a catabolic process that facilitates degradation of intracellular components in lysosomes[1] (Fig. 1). Up-regulation of autophagy to clear protein inclusions has been shown to alleviate pathogenesis of various neurodegenerative diseases and represents an attractive therapeutic approach...