Oxidative phosphorylation — an update on a new, essential target space for drug discovery in mycobacterium tuberculosis
New drugs with new mechanisms of action are urgently required to tackle the global tuberculosis epidemic. Following the FDA-approval of the ATP synthase inhibitor bedaquiline (Sirturo®), energy metabolism has become the subject of intense focus as a novel pathway to exploit for tuberculosis drug dev...
Saved in:
Main Authors: | Foo, Caroline Shi-Yan, Pethe, Kevin, Lupien, Andréanne |
---|---|
Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2020
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/138552 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Nanyang Technological University |
Language: | English |
Similar Items
-
New 2-Ethylthio-4-methylaminoquinazoline derivatives inhibiting two subunits of cytochrome bc1 in Mycobacterium tuberculosis
by: Lupien, Andréanne, et al.
Published: (2021) -
Metabolic versatility of Mycobacterium tuberculosis during infection and dormancy
by: Chang, Dorothy Pei Shan, et al.
Published: (2021) -
Mechanisms of a Mycobacterium tuberculosis active peptide
by: Rao, Komal Umashankar, et al.
Published: (2023) -
Therapeutic potential of promiscuous targets in Mycobacterium tuberculosis
by: Lee, Bei Shi, et al.
Published: (2020) -
Atomic structure of, and valine binding to the regulatory ACT domain of the Mycobacterium tuberculosis Rel protein
by: Shin, Joon, et al.
Published: (2021)