Self-association and conformational variation of NS5A domain 1 of hepatitis C virus

Direct-acting antivirals (DAAs) targeting the non-structural 5A (NS5A) protein of the hepatitis C virus (HCV) are crucial drugs that have shown exceptional clinical success in patients. However, their mode of action (MoA) remains unclear, and drug-resistant HCV strains are rapidly emerging. It is cr...

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Bibliographic Details
Main Authors: Beldar, Serap, Manimekalai, Malathy Sony Subramanian, Cho, Nam-Joon, Baek, Kwanghee, Grüber, Gerhard, Yoon, Ho Sup
Other Authors: School of Materials Science and Engineering
Format: Article
Language:English
Published: 2020
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Online Access:https://hdl.handle.net/10356/142589
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Institution: Nanyang Technological University
Language: English

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