Controlled reduction of carboxamides to alcohols or amines by zinc hydrides
New protocols for controlled reduction of carboxamides to either alcohols or amines were established using a combination of sodium hydride (NaH) and zinc halides (ZnX2 ). Use of a different halide on ZnX2 dictates the selectivity, wherein the NaH-ZnI2 system delivers alcohols and NaH-ZnCl2 gives ami...
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Main Authors: | Ong, Derek Yiren, Yen, Zhihao, Yoshii, Asami, Imbernon, Julia Revillo, Takita, Ryo, Chiba, Shunsuke |
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Other Authors: | School of Physical and Mathematical Sciences |
Format: | Article |
Language: | English |
Published: |
2020
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/144604 |
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Institution: | Nanyang Technological University |
Language: | English |
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