Controlled reduction of carboxamides to alcohols or amines by zinc hydrides

New protocols for controlled reduction of carboxamides to either alcohols or amines were established using a combination of sodium hydride (NaH) and zinc halides (ZnX2 ). Use of a different halide on ZnX2 dictates the selectivity, wherein the NaH-ZnI2 system delivers alcohols and NaH-ZnCl2 gives ami...

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Bibliographic Details
Main Authors: Ong, Derek Yiren, Yen, Zhihao, Yoshii, Asami, Imbernon, Julia Revillo, Takita, Ryo, Chiba, Shunsuke
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2020
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Online Access:https://hdl.handle.net/10356/144604
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Institution: Nanyang Technological University
Language: English

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