Carbene organic catalytic planar enantioselective macrolactonization

• Main Authors: Lv, Xiaokang, Su, Fen, Long, Hongyan, Lu, Fengfei, Zeng, Yukun, Liao, Minghong, Che, Fengrui, Wu, Xingxing, Chi, Robin Yonggui
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2024
• Subjects: Chemistry; Carbene; Diisopropylamine
• Online Access: https://hdl.handle.net/10356/174244
• Institution: Nanyang Technological University

Macrolactones exhibit distinct conformational and configurational properties and are widely found in natural products, medicines, and agrochemicals. Up to now, the major effort for macrolactonization is directed toward identifying suitable carboxylic acid/alcohol coupling reagents to address the cha...