Phenotyping of tianma-treated differentiated rat neuronal B104 cells by iTRAQ.

• Main Author: Husvinee Sundaramurthi.
• Other Authors: Klaus Heese
• Format: Final Year Project
• Language: English
• Published: 2011
• Subjects: DRNTU::Science::Biological sciences::Human anatomy and physiology::Neurobiology
• Online Access: http://hdl.handle.net/10356/42743
• Institution: Nanyang Technological University

Neurodegenerative diseases such as Alzheimer’s (AD), Parkinson’s (PD) and Huntington’s (HD) are increasingly prevalent due to the growing aging population. The basis of these diseases is the misfolding of proteins and their aggregation, which results in extensive cell death as metabolic pathways bec...