Copper-catalyzed condensation of imines and α-diazo-β-dicarbonyl compounds : modular and regiocontrolled synthesis of multisubstituted pyrroles

In the presence of a copper(II) catalyst, enolizable imines bearing various N-substituents and α-diazo-β-ketoesters undergo denitrogenative and dehydrative condensation to afford highly substituted pyrroles in moderate to good yields with exclusive regioselectivity. The reaction likely involves nucl...

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Bibliographic Details
Main Authors: Tan, Wei Wen, Yoshikai, Naohiko
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/89964
http://hdl.handle.net/10220/46433
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Institution: Nanyang Technological University
Language: English

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