Determination of encephalomyocarditis viral diabetogenicity by a putative binding site of the viral capsid protein

The molecular mechanism by which some, but not all, variants of encephalomyocarditis (EMC) virus selectively infect pancreatic beta-cells in mice and induce IDDM has been an enigma for more than a decade. We report here that the binding site of the EMC viral capsid protein VP1 determines viral diabe...

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Bibliographic Details
Main Authors: Notkins, Abner L., Yoon, Ho Sup, Jun, Hee-Sook, Kang, Yup, Kim, Ki Hwan, Yoon, Ji-Won
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2012
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Online Access:https://hdl.handle.net/10356/94163
http://hdl.handle.net/10220/7489
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Institution: Nanyang Technological University
Language: English

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