NMR and crystallographic structures of the FK506 binding domain of human malarial parasite Plasmodium vivax FKBP35
The emergence of drug-resistant malaria parasites is the major threat to effective malaria control, prompting a search for novel compounds with mechanisms of action that are different from the traditionally used drugs. The immunosuppressive drug FK506 shows an antimalarial activity. The mechanism of...
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Main Authors: | Alag, Reema, Qureshi, Insaf A, Bharatham, Nagakumar, Shin, Joon, Yoon, Ho Sup, Lescar, Julien |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2012
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/95151 http://hdl.handle.net/10220/8712 |
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Institution: | Nanyang Technological University |
Language: | English |
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