NMR and crystallographic structures of the FK506 binding domain of human malarial parasite Plasmodium vivax FKBP35

The emergence of drug-resistant malaria parasites is the major threat to effective malaria control, prompting a search for novel compounds with mechanisms of action that are different from the traditionally used drugs. The immunosuppressive drug FK506 shows an antimalarial activity. The mechanism of...

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Bibliographic Details
Main Authors: Alag, Reema, Qureshi, Insaf A, Bharatham, Nagakumar, Shin, Joon, Yoon, Ho Sup, Lescar, Julien
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2012
Subjects:
Online Access:https://hdl.handle.net/10356/95151
http://hdl.handle.net/10220/8712
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Institution: Nanyang Technological University
Language: English

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