Palladium-catalyzed, asymmetric Mizoroki–Heck reaction of benzylic electrophiles using phosphoramidites as chiral ligands
We report herein the first examples of asymmetric Mizoroki–Heck reactions using benzyl electrophiles. A new phosphoramidite was identified to be an effective chiral ligand in the palladium–catalyzed reaction. The reaction is compatible with polar functional groups and can be readily scaled up. Sever...
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| Main Authors: | , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2013
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| Online Access: | https://hdl.handle.net/10356/97595 http://hdl.handle.net/10220/11228 |
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| Institution: | Nanyang Technological University |
| Language: | English |