High expression of intratumoral stromal proteins is associated with chemotherapy resistance in breast cancer

• Main Authors: Wang, T, Srivastava, S, Hartman, M, Buhari, S.A, Chan, C.-W, Iau, P, Khin, L.W, Wong, A, Tan, S.-H, Goh, B.-C, Lee, S.-C
• Other Authors: CANCER SCIENCE INSTITUTE OF SINGAPORE
• Format: Article
• Published: 2020
• Subjects: alpha smooth muscle actin; beta1 integrin; docetaxel; doxorubicin; estrogen receptor; FN protein; mammalian target of rapamycin; oncoprotein; SPARC protein; THBS1 protein; TNC protein; unclassified drug; MTOR protein, human; target of rapamycin kinase; tenascin; thrombospondin 1; thrombospondin-1, human; Article; breast cancer; breast surgery; cancer adjuvant therapy; cancer growth; cancer resistance; cancer survival; clinical feature; cohort analysis; controlled study; drug efficacy; female; human; human tissue; immunohistochemistry; major clinical study; MCF 7 cell line; multiple cycle treatment; outcome assessment; overall survival; phase 2 clinical trial; prediction; protein determination; protein expression; protein function; randomized controlled trial; tumor biopsy; upregulation; adult; aged; breast tumor; chemistry; drug resistance; middle aged; mortality; pathology; physiology; signal transduction; tumor cell line; Adult; Aged; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Humans; Integrin beta1; Middle Aged; Signal Transduction; Tenascin; Thrombospondin 1; TOR Serine-Threonine Kinases
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/174109
• Institution: National University of Singapore

10.18632/oncotarget.10894