The Plasmodium PI(4)K inhibitor KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites

• Main Authors: Dembele, L, Ang, X, Chavchich, M, Bonamy, G.M.C, Selva, J.J, Lim, M.Y.-X, Bodenreider, C, Yeung, B.K.S, Nosten, F, Russell, B.M, Edstein, M.D, Straimer, J, Fidock, D.A, Diagana, T.T, Bifani, P
• Other Authors: MICROBIOLOGY AND IMMUNOLOGY
• Format: Article
• Published: 2020
• Subjects: antimalarial agent; artemisinin; artemisinin derivative; dihydroartemisinin; pyrazine derivative; animal; cell cycle checkpoint; drug effect; drug resistance; human; malaria falciparum; parasitology; pathogenicity; Plasmodium falciparum; Animals; Antimalarials; Artemisinins; Cell Cycle Checkpoints; Drug Resistance; Humans; Malaria, Falciparum; Pyrazines
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/178319
• Institution: National University of Singapore

10.1038/s41598-017-02440-6