Intracellular A? pathology and early cognitive impairments in a transgenic rat overexpressing human amyloid precursor protein: A multidimensional study

• Main Authors: Iulita, M.F, Allard, S, Richter, L, Munter, L.M, Ducatenzeiler, A, Weise, C, DoCarmo, S, Klein, W.L, Multhaup, G, Cuello, A.C
• Other Authors: DEPT OF PHARMACOLOGY
• Format: Article
• Published: 2020
• Subjects: amyloid beta protein; amyloid beta protein[1-40]; amyloid beta-protein (1-42); amyloid precursor protein; peptide fragment; secretase; animal; auditory stimulation; brain; cerebrospinal fluid; cognitive defect; conditioning; disease model; fear; gene expression regulation; genetics; human; intracellular fluid; metabolism; mutation; pain measurement; pathology; physiology; rat; recognition; regression analysis; transgenic rat; adverse effects; Acoustic Stimulation; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Brain; Cognition Disorders; Conditioning (Psychology); Disease Models, Animal; Fear; Gene Expression Regulation; Humans; Intracellular Fluid; Mutation; Pain Measurement; Peptide Fragments; Rats; Rats, Transgenic; Recognition (Psychology); Regression Analysis
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/182028
• Institution: National University of Singapore

10.1186/2051-5960-2-61