Telomere shortening and cell senescence induced by perylene derivatives in A549 human lung cancer cells

Telomere shortening and cell senescence induced by perylene derivatives in A549 human lung cancer cells

Cancer cells evade replicative senescence by re-expressing telomerase, which maintains telomere length and hence chromosomal integrity. Telomerase inhibition would lead cancer cells to senesce and therefore prevent cancer cells from growing indefinitely. G-quadruplex ligands can attenuate telomerase...

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書目詳細資料
Main Authors:	Taka T., Huang L., Wongnoppavich A., Tam-Chang S.-W., Lee T.R., Tuntiwechapikul W.
格式:	Article
語言:	English
出版:	2014
在線閱讀:	http://www.scopus.com/inward/record.url?eid=2-s2.0-84873312526&partnerID=40&md5=b55d40a92e31ccb4ff50cacfcac3b9c2 http://www.ncbi.nlm.nih.gov/pubmed/23321015 http://cmuir.cmu.ac.th/handle/6653943832/4017
標簽:	添加標簽沒有標簽, 成為第一個標記此記錄!
機構:	Chiang Mai University
語言:	English

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