EMMPRIN reduction via scFv-M6-1B9 intrabody affects α3β1- integrin and MCT1 functions and results in suppression of progressive phenotype in the colorectal cancer cell line Caco-2
Extracellular matrix metalloproteinase inducer (EMMPRIN) exhibits overexpression in various cancers and promotes cancer progression and metastasis via the interaction with its associated molecules. The scFv-M6-1B9 intrabody has a potential ability to reduce EMMPRIN cell surface expression. However,...
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Main Authors: | S. Sangboonruang, P. Thammasit, N. Intasai, W. Kasinrerk, C. Tayapiwatana, K. Tragoolpua |
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Format: | Journal |
Published: |
2018
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Online Access: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84903593918&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/45468 |
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Institution: | Chiang Mai University |
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