Effects of the iron chelator deferiprone and the T-type calcium channel blocker efonidipine on cardiac function and Ca²⁺regulation in iron-overloaded thalassemic mice

• Main Authors: Juthamas Khamseekaew, Sirinart Kumfu, Siripong Palee, Suwakon Wongjaikam, Somdet Srichairatanakool, Suthat Fucharoen, Siriporn C. Chattipakorn, Nipon Chattipakorn
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85044378999&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/58243
• Institution: Chiang Mai University

© 2018 Elsevier Ltd Although disturbance of cardiac Ca2+regulation is involved in the pathophysiology of iron-overload cardiomyopathy, the obvious mechanisms involved in the dysregulation of iron-induced cardiac Ca2+are unclear. Moreover, the roles of the iron chelator deferiprone and the T-type cal...