Zinc finger protein designed to target 2-long terminal repeat junctions interferes with human immunodeficiency virus integration
Integration of the human immunodeficiency virus type 1 (HIV-1) genome into the host chromosome is a vital step in the HIV life cycle. The highly conserved cytosine-adenine (CA) dinucleotide sequence immediately upstream of the cleavage site is crucial for integrase (IN) activity. As this viral enzym...
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Main Authors: | Sakkhachornphop S., Barbas C.F., Keawvichit R., Wongworapat K., Tayapiwatana C. |
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Format: | Article |
Language: | English |
Published: |
2014
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Online Access: | http://www.scopus.com/inward/record.url?eid=2-s2.0-84866325679&partnerID=40&md5=8566b0689be01855e3a4fb2b8a76e98c http://cmuir.cmu.ac.th/handle/6653943832/909 |
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Institution: | Chiang Mai University |
Language: | English |
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