Binding of flavivirus nonstructural protein NS1 to C4b binding protein modulates complement activation

The complement system plays a pivotal protective role in the innate immune response to many pathogens including flaviviruses. Flavivirus nonstructural protein 1 (NS1) is a secreted nonstructural glycoprotein that accumulates in plasma to high levels and is displayed on the surface of infected cells...

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Bibliographic Details
Main Authors: Panisadee Avirutnan, Richard E. Hauhart, Pawit Somnuke, Anna M. Blom, Michael S. Diamond, John P. Atkinson
Other Authors: Washington University in St. Louis, School of Medicine
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/12028
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Institution: Mahidol University

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