Binding of flavivirus nonstructural protein NS1 to C4b binding protein modulates complement activation
The complement system plays a pivotal protective role in the innate immune response to many pathogens including flaviviruses. Flavivirus nonstructural protein 1 (NS1) is a secreted nonstructural glycoprotein that accumulates in plasma to high levels and is displayed on the surface of infected cells...
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Main Authors: | Panisadee Avirutnan, Richard E. Hauhart, Pawit Somnuke, Anna M. Blom, Michael S. Diamond, John P. Atkinson |
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Other Authors: | Washington University in St. Louis, School of Medicine |
Format: | Article |
Published: |
2018
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/12028 |
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Institution: | Mahidol University |
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