Effect of iron overload on furin expression in wild-type and β-thalassemic mice

Furin is a proprotein convertase enzyme. In the liver, it cleaves prohepcidin to form active hepcidin-25, which regulates systemic iron homeostasis. Hepcidin deficiency is a component of several iron overload disorders, including β-thalassemia. Several studies have identified factors that repress he...

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Main Authors: Surasak Wichaiyo, Paranee Yatmark, Ronald Enrique Morales Vargas, Pimtip Sanvarinda, Saovaros Svasti, Suthat Fucharoen, Noppawan Phumala Morales
Other Authors: Mahidol University. Institute of Molecular Biosciences. Thalassemia Research Center
Format: Article
Language:English
Published: 2016
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/1839
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Institution: Mahidol University
Language: English

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