Effect of iron overload on furin expression in wild-type and β-thalassemic mice
Furin is a proprotein convertase enzyme. In the liver, it cleaves prohepcidin to form active hepcidin-25, which regulates systemic iron homeostasis. Hepcidin deficiency is a component of several iron overload disorders, including β-thalassemia. Several studies have identified factors that repress he...
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| Main Authors: | , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/1839 |
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| Institution: | Mahidol University |
| Language: | English |