Independent evolution of pyrimethamine resistance in Plasmodium falciparum isolates in Melanesia
Pyrimethamine resistance in Plasmodium falciparum has previously been shown to have emerged once in Southeast Asia, from where it spread to Africa. Pyrimethamine resistance in this parasite is known to be conferred by mutations in the gene encoding dihydrofolate reductase (dhfr). We have analyzed po...
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Main Authors: | Toshihiro Mita, Kazuyuki Tanabe, Nobuyuki Takahashi, Takahiro Tsukahara, Hideaki Eto, Lek Dysoley, Hiroshi Ohmae, Kiyoshi Kita, Srivicha Krudsood, Sornchai Looareesuwan, Akira Kaneko, Anders Björkman, Takatoshi Kobayakawa |
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Other Authors: | Tokyo Women's Medical University |
Format: | Article |
Published: |
2018
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/24982 |
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Institution: | Mahidol University |
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