Base-catalyzed diastereodivergent thia-Michael addition to chiral β-trifluoromethyl-α,β-unsaturated N-acylated oxazolidin-2-ones

Base-catalyzed diastereodivergent thia-Michael addition to chiral β-trifluoromethyl-α,β-unsaturated N-acylated oxazolidin-2-ones

Base-catalyzed diastereodivergent thia-Michael addition of thiols to chiral β-trifluoromethyl-α,β-unsaturated N-acylated oxazolidin-2-ones is reported. By tuning the base-catalyst (i-Pr2NEt, DABCO, or P2-t-Bu), a range of chiral thia-Michael adducts was synthesized in good yields with high diastereo...

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Bibliographic Details
Main Author:	Racochote S.
Other Authors:	Mahidol University
Format:	Article
Published:	2023
Subjects:	Chemistry
Online Access:	https://repository.li.mahidol.ac.th/handle/123456789/90037
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	Mahidol University

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