A STUDY OF THE TRANSCRIPTIONAL REGULATION OF CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX GENES AND THEIR UP-REGULATION BY INTERFERONS

by LIM SIEW PHENG
Published 2020

Conformational flexibility of the dengue virus RNA-dependent RNA polymerase revealed by a complex with an inhibitor

by Yap, Lijian, Lescar, Julien, Noble, Christian G., Lim, Siew Pheng, Chen, Yen-Liang, Liew, Chong Wai, Shi, Pei-Yong
Published 2015

NS5 from dengue virus serotype 2 can adopt a conformation analogous to that of its Zika virus and Japanese encephalitis virus homologues

by El Sahili, Abbas, Soh, Sherryl Tingjin, Schiltz, Jonas, Gharbi-Ayachi, Aïcha, Seh, Cheah Chen, Shi, Pei-Yong, Lim, Siew Pheng, Lescar, Julien
Published 2020

Molecular basis for specific viral RNA recognition and 2' -O-ribose methylation by the dengue virus nonstructural protein 5 (NS5)

by Zhao, Yongqian, Soh, Tingjin Sherryl, Lim, Siew Pheng, Chung, Ka Yan, Swaminathan, Kunchithapadam, Vasudevan, Subhash G., Shi, Pei-Yong, Lescar, Julien, Luo, Dahai
Published 2016

Flexibility of NS5 Methyltransferase-Polymerase Linker Region Is Essential for Dengue Virus Replication

by Zhao, Yongqian, Soh, Tingjin Sherryl, Chan, Kitti Wing Ki, Fung, Sarah Suet Yin, Swaminathan, Kunchithapadam, Lim, Siew Pheng, Shi, Pei-Yong, Huber, Thomas, Lescar, Julien, Luo, Dahai, Vasudevan, Subhash G.
Published 2015

A crystal structure of the dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication

by Zhao, Yongqian, Soh, Tingjin Sherryl, Zheng, Jie, Chan, Kitti Wing Ki, Phoo, Wint Wint, Lee, Chin Chin, Tay, Moon Y. F., Swaminathan, Kunchithapadam, Cornvik, Tobias Carl, Lim, Siew Pheng, Shi, Pei-Yong, Lescar, Julien, Vasudevan, Subhash G., Luo, Dahai
Published 2015

Two RNA tunnel inhibitors bind in highly conserved sites in dengue virus NS5 polymerase : structural and functional studies

by Arora, Rishi, Liew, Chong Wai, Soh, Sherryl Tingjin, Otoo, Dorcas Adobea, Seh, Cheah Chen, Yue, Kimberley, Shahul Nilar, Wang, Gang, Yokokawa, Fumiaki, Noble, Christian G., Chen, Yen Liang, Shi, Pei-Yong, Lescar, Julien, Smith, Thomas M., Benson, Timothy E., Lim, Siew Pheng
Published 2021

Functional and structural characterization of the inter-domain linker region of the dengue virus serotype 4 NS5 protein

by Ting, Trinda Anne
Published 2015