A whole cell pathway screen reveals seven novel chemosensitizers to combat chloroquine resistant malaria
Due to the widespread prevalence of resistant parasites, chloroquine (CQ) was removed from front-line antimalarial chemotherapy in the 1990s despite its initial promise of disease eradication. Since then, resistance-conferring mutations have been identified in transporters such as the PfCRT, that...
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Main Authors: | Ch'ng, Jun-Hong, Mok, Sachel, Bozdech, Zbynek, Lear, Martin James, Boudhar, Aicha, Russell, Bruce, Nosten, Francois, Tan, Kevin Shyong-Wei |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2013
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/100940 http://hdl.handle.net/10220/16522 |
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Institution: | Nanyang Technological University |
Language: | English |
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