Targeting the cytochrome oxidases for drug development in mycobacteria
Mycobacterium tuberculosis strictly depends on oxygen to multiply, and the terminal oxidases are a vital part of the oxidative phosphorylation pathway. The bacterium possesses two aerobic respiratory branches: a cytochrome bcc-aa3 and a bacteria-specific cytochrome bd oxidase. The identification of...
Saved in:
Main Authors: | Lee, Bei Shi, Sviriaeva, Ekaterina, Pethe, Kevin |
---|---|
Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2020
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/139336 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Nanyang Technological University |
Language: | English |
Similar Items
-
Features and functional importance of key residues of the Mycobacterium tuberculosis cytochrome bd oxidase
by: Sviriaeva, Ekaterina, et al.
Published: (2021) -
Insights into the mechanism, structure and potential as drug target of the mycobacterial bd-type terminal oxidase
by: Ekaterina, Sviriaeva
Published: (2022) -
Targeting the menaquinol binding loop of mycobacterial cytochrome bd oxidase
by: Harikishore, Amaravadhi, et al.
Published: (2020) -
Sensitivity of mycobacterium leprae to telacebec
by: Lahiri, Ramanuj, et al.
Published: (2022) -
Therapeutic potential of promiscuous targets in Mycobacterium tuberculosis
by: Lee, Bei Shi, et al.
Published: (2020)