Chelating phosphine-N-heterocyclic carbene platinum complexes via catalytic asymmetric hydrophosphination and their cytotoxicity toward MKN74 and MCF7 cancer cell lines
A series of activated vinyl azoles was hydrophosphinated in the presence of a chiral palladacycle catalyst under mild conditions to give enantioenriched phosphine azoles with moderate enantioselectivities and yields. The racemic phosphine azoles were transformed into eleven novel chelating phosphine...
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| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2022
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/157005 |
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| Institution: | Nanyang Technological University |
| Language: | English |