Understanding the role of drug efflux transporters in vincristine-resistant acute lymphoblastic leukaemia cells.
Cell proliferation is an integral process in ensuring leukemic cell survival. Microtubules, essential cytoskeleton components and important players in mitosis, makes them effective therapeutic target in leukaemia. The vinca alkaloid, vincristine (VCR), specifically disrupts microtubule dynamics, cau...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2013
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| Online Access: | http://hdl.handle.net/10356/52941 |
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| Institution: | Nanyang Technological University |
| Language: | English |