Study on catalytic properties of flap structure : specific endonuclease 1 and establishment of new platforms for screening its inhibitors
Flap structure-specific endonuclease 1 (FEN 1) is known to be essential for reproduction and development of eukaryotic cells. During DNA replication in cell division, a 5' flap structure is generated by polymerase 8. FENl subsequently emerges, specifically recognizes the produced flap struct...
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| Format: | Theses and Dissertations |
| Language: | English |
| Published: |
2016
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| Online Access: | https://hdl.handle.net/10356/68899 |
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| Institution: | Nanyang Technological University |
| Language: | English |