Is c-myc super-enhancer invasion associated with aberrant chromatin interactions in cancer?
c-Myc is an oncogenic transcription factor being over-expressed in approximately 70% of human cancers. However, c-Myc is notoriously an “undruggable’ target and its inhibition is complex. In general, super-enhancer is a collection of enhancers with a stronger enrichment of transcription factor bindi...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2017
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| Online Access: | http://hdl.handle.net/10356/70881 |
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| Institution: | Nanyang Technological University |
| Language: | English |