Knockdown of two ER stress-related genes and their effect on pancreatic beta-cell function
ER stress is associated with beta-cell dysfunction in Type 2 diabetes (T2D). A recent study by Dorajoo and colleagues show that several ER stress implicated genes including HSP90B1, DNAJC3, UCHL1 are upregulated in pancreatic islets from Singaporean-Chinese donors. Besides these genes, OLMALINC,...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2018
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| Online Access: | http://hdl.handle.net/10356/74672 |
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| Institution: | Nanyang Technological University |
| Language: | English |