Access to pyridines via DMAP-catalyzed activation of α-chloro acetic ester to react with unsaturated imines

Access to pyridines via DMAP-catalyzed activation of α-chloro acetic ester to react with unsaturated imines

Facile access to trisubstituted pyridines from α-chloro acetic ester and unsaturated imines is achieved. DMAP-catalyzed activation of ester to form an enolate intermediate constitutes a key reaction step. On the application side, the wide availability and low cost of the substrates and catalysts mak...

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Main Authors: Chi, Robin Yonggui, Hao, Lin, Chen, Xingkuan, Chen, Shaojin, Jiang, Ke, Torres, Jaume
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2014
Subjects:
DRNTU::Science::Biological sciences
Online Access:https://hdl.handle.net/10356/79664
http://hdl.handle.net/10220/23927
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-796642023-02-28T16:58:08Z Access to pyridines via DMAP-catalyzed activation of α-chloro acetic ester to react with unsaturated imines Chi, Robin Yonggui Hao, Lin Chen, Xingkuan Chen, Shaojin Jiang, Ke Torres, Jaume School of Physical and Mathematical Sciences School of Biological Sciences DRNTU::Science::Biological sciences Facile access to trisubstituted pyridines from α-chloro acetic ester and unsaturated imines is achieved. DMAP-catalyzed activation of ester to form an enolate intermediate constitutes a key reaction step. On the application side, the wide availability and low cost of the substrates and catalysts make this method very attractive. 2014-10-01T02:09:37Z 2019-12-06T13:30:25Z 2014-10-01T02:09:37Z 2019-12-06T13:30:25Z 2014 2014 Journal Article Hao, L., Chen, X., Chen, S., Jiang, K., Torres, J., & Chi, Y. R. (2014). Access to pyridines via DMAP-catalyzed activation of α-chloro acetic ester to react with unsaturated imines. Organic chemistry frontiers, 1(2), 148-150. https://hdl.handle.net/10356/79664 http://hdl.handle.net/10220/23927 10.1039/C3QO00045A 179797 en Organic chemistry frontiers © 2014 the Partner Organisations. 3 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic DRNTU::Science::Biological sciences
spellingShingle DRNTU::Science::Biological sciences
Chi, Robin Yonggui
Hao, Lin
Chen, Xingkuan
Chen, Shaojin
Jiang, Ke
Torres, Jaume
Access to pyridines via DMAP-catalyzed activation of α-chloro acetic ester to react with unsaturated imines
description Facile access to trisubstituted pyridines from α-chloro acetic ester and unsaturated imines is achieved. DMAP-catalyzed activation of ester to form an enolate intermediate constitutes a key reaction step. On the application side, the wide availability and low cost of the substrates and catalysts make this method very attractive.
author2 School of Physical and Mathematical Sciences
author_facet School of Physical and Mathematical Sciences
Chi, Robin Yonggui
Hao, Lin
Chen, Xingkuan
Chen, Shaojin
Jiang, Ke
Torres, Jaume
format Article
author Chi, Robin Yonggui
Hao, Lin
Chen, Xingkuan
Chen, Shaojin
Jiang, Ke
Torres, Jaume
author_sort Chi, Robin Yonggui
title Access to pyridines via DMAP-catalyzed activation of α-chloro acetic ester to react with unsaturated imines
title_short Access to pyridines via DMAP-catalyzed activation of α-chloro acetic ester to react with unsaturated imines
title_full Access to pyridines via DMAP-catalyzed activation of α-chloro acetic ester to react with unsaturated imines
title_fullStr Access to pyridines via DMAP-catalyzed activation of α-chloro acetic ester to react with unsaturated imines
title_full_unstemmed Access to pyridines via DMAP-catalyzed activation of α-chloro acetic ester to react with unsaturated imines
title_sort access to pyridines via dmap-catalyzed activation of α-chloro acetic ester to react with unsaturated imines
publishDate 2014
url https://hdl.handle.net/10356/79664
http://hdl.handle.net/10220/23927
_version_ 1759856326204194816

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