Access to pyridines via DMAP-catalyzed activation of α-chloro acetic ester to react with unsaturated imines
Facile access to trisubstituted pyridines from α-chloro acetic ester and unsaturated imines is achieved. DMAP-catalyzed activation of ester to form an enolate intermediate constitutes a key reaction step. On the application side, the wide availability and low cost of the substrates and catalysts mak...
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| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/79664 http://hdl.handle.net/10220/23927 |
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| Institution: | Nanyang Technological University |
| Language: | English |