Deletion of a unique loop in the mycobacterial F-ATP synthase γ subunit sheds light on its inhibitory role in ATP hydrolysis-driven H+ pumping

The F1FO-ATP synthase is one of the enzymes that is essential to meet the energy requirement of both the proliferating aerobic and hypoxic dormant stages of the life cycle of mycobacteria. Most F-ATP synthases consume ATP in the α3:β3 headpiece to drive the γ subunit, which couples ATP cleavage with...

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Bibliographic Details
Main Authors: Hotra, Adam, Suter, Manuel, Biuković, Goran, Priya, Ragunathan, Kundu, Subhashri, Dick, Thomas, Grüber, Gerhard
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2016
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Online Access:https://hdl.handle.net/10356/83414
http://hdl.handle.net/10220/41395
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Institution: Nanyang Technological University
Language: English

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