Molecular basis of Bcl-XL-p53 interaction : insights from molecular dynamics simulations

Bcl-XL, an antiapoptotic Bcl-2 family protein, plays a central role in the regulation of the apoptotic pathway. Heterodimerization of the antiapoptotic Bcl-2 family proteins with the proapoptotic family members such as Bad, Bak, Bim and Bid is a crucial step in the apoptotic regulation. In add...

Full description

Saved in:
Bibliographic Details
Main Authors: Bharatham, Nagakumar, Chi, Seung-Wook, Yoon, Ho Sup
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2012
Subjects:
Online Access:https://hdl.handle.net/10356/93655
http://hdl.handle.net/10220/7512
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English

Similar Items