Enhanced separation and characterization of deamidated peptides with RP-ERLIC-based multidimensional chromatography coupled with tandem mass spectrometry

Deamidation of asparaginyl residues in proteins produces a mixture of asparaginyl, n-aspartyl, and isoaspartyl residues, which affects the proteins’ structure, function, and stability. Thus, it is important to identify and quantify the products to evaluate the effects in biological systems. It is st...

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Main Authors: Hao, Piliang, Qian, Jingru, Dutta, Bamaprasad, Cheow, Esther Sok Hwee, Sim, Kae Hwan, Meng, Wei, Alpert, Andrew, Sze, Siu Kwan, Adav, Sunil S.
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/95847
http://hdl.handle.net/10220/11322
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Institution: Nanyang Technological University
Language: English

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