VSL#3 Resets Insulin Signaling and Protects against NASH and Atherosclerosis in a Model of Genetic Dyslipidemia and Intestinal Inflammation

• Main Authors: Mencarelli A., Cipriani S., Renga B., Bruno A., D'Amore C., Distrutti E., Fiorucci S.
• Other Authors: DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
• Published: 2019
• Subjects: dextran sulfate; farnesoid X receptor; peroxisome proliferator activated receptor gamma; vitamin D receptor; VSL3; adipose tissue; animal cell; animal experiment; animal model; animal tissue; antiinflammatory activity; aorta atherosclerosis; article; controlled study; disease severity; drug efficacy; dyslipidemia; enteritis; histopathology; insulin resistance; intestine mucosa permeability; liver protection; male; mesentery; mouse; nonalcoholic fatty liver; nonhuman; transactivation; treatment duration; Animals; Apolipoproteins E; Atherosclerosis; Dyslipidemias; Fatty Liver; Inflammation; Insulin Resistance; Intestines; Male; Mice; Mice, Knockout; Probiotics; Signal Transduction; Mus
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161730
• Institution: National University of Singapore

10.1371/journal.pone.0045425