Acute exposure to tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) causes hepatic inflammation and leads to hepatotoxicity in zebrafish

• Main Authors: Liu, C, Su, G, Giesy, J.P, Letcher, R.J, Li, G, Agrawal, I, Li, J, Yu, L, Wang, J, Gong, Z
• Other Authors: BIOLOGICAL SCIENCES
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: flame retardant; fluorescent protein 583; germinal center kinases; organophosphorus compound; photoprotein; protein serine threonine kinase; reduced nicotinamide adenine dinucleotide (phosphate) dehydrogenase (quinone); toll like receptor; tris(1,3-dichloro-2-propyl)phosphate; water pollutant; zebrafish protein; animal; drug effects; endoplasmic reticulum stress; gene expression regulation; genetics; growth, development and aging; inflammation; larva; liver; male; metabolism; neutrophil; neutrophil chemotaxis; nonmammalian embryo; pathology; reporter gene; toxic hepatitis; toxicity; zebra fish; Animals; Chemical and Drug Induced Liver Injury; Embryo, Nonmammalian; Endoplasmic Reticulum Stress; Flame Retardants; Gene Expression Regulation, Developmental; Genes, Reporter; Inflammation; Larva; Liver; Luminescent Proteins; Male; NAD(P)H Dehydrogenase (Quinone); Neutrophil Infiltration; Neutrophils; Organophosphorus Compounds; Protein-Serine-Threonine Kinases; Toll-Like Receptors; Water Pollutants, Chemical; Zebrafish; Zebrafish Proteins
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175445
• Institution: National University of Singapore

10.1038/srep19045