Sequence- and structure-specific targeting of RNAs by short nucleobase-modified dsRNA-Binding PNAs Incorporating A-U pair-recognizing fluorescent light-up benzothiophene uracil and...

by Shivakumar Krishna Manchugondanahalli
Published 2020

Incorporating G-C pair-recognizing Guanidinium into PNAs for sequence and structure specific recognition of dsRNAs over dsDNAs and ssRNAs

by Krishna, Manchugondanahalli S., Wang, Zhenzhang, Zheng, Liangzhen, Bowry, Jogesh, Ong, Alan Ann Lerk, Mu, Yuguang, Prabakaran, Mookkan, Chen, Gang
Published 2021

Tertiary base triple formation in the SRV-1 frameshifting pseudoknot stabilizes secondary structure components

by Yang, Lixia, Toh, Desiree-Faye Kaixin, Krishna, Manchugondanahalli Shivakumar, Zhong, Zhensheng, Liu, Yiyao, Wang, Shaomeng, Gong, Yubin, Chen, Gang
Published 2021

Sequence- and structure-specific probing of RNAs by short nucleobase-modified dsRNA-binding PNAs incorporating a fluorescent light-up uracil analog

by Krishna, Manchugondanahalli Shivakumar, Toh, Desiree-Faye Kaixin, Meng, Zhenyu, Ong, Alan Ann Lerk, Wang, Zhenzhang, Lu, Yunpeng, Xia, Kelin, Prabakaran, Mookkan, Chen, Gang
Published 2021

Incorporating uracil and 5-halouracils into short peptide nucleic acids for enhanced recognition of A–U pairs in dsRNAs

by Patil, Kiran M., Ong, Alan Ann Lerk, Krishna, Manchugondanahalli Shivakumar, Toh, Desiree-Faye Kaixin, Yuan, Zhen, Meng, Zhenyu, Shu, Zhiyu, Zhang, Haiping, Lu, Lanyuan, Lu, Yunpeng, Chen, Gang
Published 2019

General recognition of U‑G, U‑A, and C‑G pairs by double-stranded RNA-binding PNAs incorporated with an artificial nucleobase

by Ong, Alan Ann Lerk, Toh, Desiree-Faye Kaixin, Patil, Kiran M., Meng, Zhenyu, Yuan, Zhen, Krishna, Manchugondanahalli S., Devi, Gitali, Haruehanroengra, Phensinee, Lu, Yunpeng, Xia, Kelin, Okamura, Katsutomo, Sheng, Jia, Chen, Gang
Published 2021

A short chemically modified dsRNA-Binding PNA (dbPNA) inhibits influenza viral replication by targeting viral RNA panhandle structure

by Kesy, Julita, Patil, Kiran M., Kumar, Subaschandrabose Rajesh, Shu, Zhiyu, Yong, Hui Yee, Zimmermann, Louis, Ong, Alan Ann Lerk, Toh, Desiree-Faye Kaixin, Krishna, Manchugondanahalli S., Yang, Lixia, Decout, Jean-Luc, Luo, Dahai, Prabakaran, Mookkan, Chen, Gang, Kierzek, Elzbieta
Published 2021

Recognition of RNA secondary structures with a programmable peptide nucleic acid-based platform

by Lu, Rongguang, Deng, Liping, Lian, Yun, Ke, Xin, Yang, Lixia, Xi, Kun, Ong, Alan Ann Lerk, Chen, Yanyu, Zhou, Hanting, Meng, Zhenyu, Lin, Ruiyu, Fan, Shijian, Liu, Yining, Toh, Desiree-Faye Kaixin, Zhan, Xuan, Krishna, Manchugondanahalli S., Patil, Kiran M., Lu, Yunpeng, Liu, Zheng, Zhu, Lizhe, Wang, Hongwei, Li, Guobao, Chen, Gang
Published 2024

Targeting RNA Editing of Antizyme Inhibitor 1: a Potential Oligonucleotide-Based Antisense Therapy for Cancer.

by Tai Tay, Daryl Jin, Song, Yangyang, Peng, Boya, Toh, Tan Boon, Hooi, Lissa, Kaixin Toh, Desiree-Faye, Hong, HuiQi, Tang, Sze Jing, Han, Jian, Gan, Wei Liang, Man Chan, Tim Hon, Krishna, Manchugondanahalli S, Patil, Kiran M, Maraswami, Manikantha, Loh, Teck Peng, Dan, Yock Young, Zhou, Lei, Bonney, Glenn Kunnath, Kah-Hoe Chow, Pierce, Chen, Gang, Kai-Hua Chow, Edward, Le, Minh Tn, Chen, Leilei
Published 2021